Buy "life extension" online - search for the best price - compare prices

Throughout life, cells known as osteoblasts construct bone matrix and fill it with calcium. At the same time, osteoclasts work just as busily to tear down and resorb bone. This fine balance is regulated by many factors, including systemic hormones and cytokines. Bone mass reaches its peak by the middle of the third decade of life and plateaus for about ten years, during which time bone turnover is constant, with bone formation approximately equaling bone resorption. As our bodies age, this fine balance is lost. As the relative hormone levels shift in midlife - more drastically in women than in men - the osteoclasts gain the upper hand and bone mass begins to dwindle. Some bone is already being lost by the time women reach menopause, but the rate of loss can increase up to tenfold during the first five years after menopause. Bone density loss is not just associated with calcium deficiency, but also with an insufficient intake of a host of other nutrients including magnesium and vitamin D3. In order for calcium to help maintain healthy bones, adequate amounts of vitamin D3, zinc, magnesium, manganese, and other nutrients should be available so that calcium and phosphorus can be incorporated into the bone matrix. Additionally, many forms of calcium are not particularly well absorbed. Calcium is the most abundant mineral in the body ... primarily found in the bones and teeth. In bone formation, calcium forms crystals that provide strength to maturing bone. Peak bone mass is usually achieved when people are in their 20s. While loss of bone mineral density is more commonly experienced by women, aging men can also have this issue. Both men and women may experience significant deficits of magnesium if they do not supplement. Bone Restore now contains magnesium citrate, which is one of the most absorbable forms of magnesium. Magnesium is not only needed to maintain strong bones, but it is critical to promoting a healthy vascular system. In fact, magnesium is critical for facilitating hundreds of enzymatic reactions that our bodies require to maintain optimal health. To overcome the impediments that preclude aging adults from achieving optimal calcium status, Life Extension offers a proprietary comprehensive mineral formula called Bone Restore which has been designed to support healthy bone density and strength. Bone Restore provides 1200 milligrams of elemental calcium from three different forms, along with the critically important nutrients magnesium, boron, zinc, silicon, manganese and vitamin D needed for healthy bones. In fact, the boron in this formula, called FruiteX B OsteoBoron, is a boron/carbohydrate complex, similar to what is found in fruits and vegetables and is more bioavailable than boron citrate. Scientific research has established the beneficial effects of boron on the strength of bones and joints. One reason why aging people experience bone mineral density loss even though they are taking calcium supplements is that they may not be absor

Bone Restore combines critical bone boosting nutrients into one superior formula. Bone Restore includes highly absorbable forms of calcium and boron, along with vitamin D3, magnesium, zinc, manganese, and silicon. Bone Restore is now available with or without vitamin K2 (MK-7). Bone Restore contains magnesium citrate, which is one of the most absorbable forms of magnesium. Maintaining an optimal vitamin D blood level also helps maximize calcium absorption.

Bone Restore combines critical bone boosting nutrients into one superior formula. Bone Restore includes highly absorbable forms of calcium and boron, along with vitamin D3, magnesium, zinc, manganese, and silicon. Bone Restore is now available with or without vitamin K2 (MK-7). Bone Restore contains magnesium citrate, which is one of the most absorbable forms of magnesium. Maintaining an optimal vitamin D blood level also helps maximize calcium absorption.

The use of diets high in collagen to improve bone health dates back to ancient cultures. Life Extension brings you this exciting formulation with KoAct, a patented chelated form of calcium and collagen designed to maintain optimal bone health. KoAct helps maintain bone strength and mineral density. This remarkable ingredient allows for greater strength and flexibility, so your bones can absorb energy, reducing the risk of age-related injuries. Additional plant extracts from bamboo and dried plum have also been added for their bone-protective minerals and polyphenols. Bone Strength Formula with KoAct contains the following ingredients: Vitamin D3 Facilitates absorption of calcium into the bloodstream. Regulates how much calcium enters and leaves bone tissue. Helps regulate healthy cell division and differentiation. Functions as a vital co-factor in bone mineralization through the absorption of calcium and phosphorus. Calcium KoAct is a unique patented chelated compound of calcium and hydrolyzed collagen peptides (type I collagen) designed to enhance collagen support and turnover while supporting optimal bone mineral density and strength, Magnesium A critical component of our skeleton, with 50-60% of totally body magnesium found in bone Positively influences the bone mineral matrix and its ability to metabolize minerals needed for repair and rebuilding. Silicon Plays an important role in bone formation through the synthesis and/or stabilization of collagen. Dried Plum Supports osteoblast (bone building cells) activity and function by upregulating cell-signaling compounds (Runx2, Osterix and IGF-1) and enhancing expression of an enzyme (lysyl oxidase) that is involved in collagen cross-linking.

Booster Softgels contain nutrients that support arterial health and provide comprehensive protection from the effects of oxidative damage caused by free radical assaults. Like the Super Booster formula, Booster Softgels provide significant cost savings over purchasing each ingredient separately. This particular formula is still being offered because it does not contain vitamin K. Coumadin (Warfarin) drug users are advised to avoid high-dose vitamin K supplements. Just one Booster softgel provides: Gamma Tocopherol ? If one consumes only alpha tocopherol, the critically important gamma tocopherol is displaced from cells within the body. While alpha tocopherol vitamin E suppresses lipid peroxidation , the gamma tocopherol form quenches the dangerous peroxynitrite free radical. It is especially important for those who take vitamin E supplements to make sure they consume at least 200 mg of gamma tocopherol daily. Sesame Lignans ? Sesame lignans augment the antioxidant effects of both alpha and gamma tocopherol. In a human study, gamma tocopherol plus sesame lignans were 25% more effective in suppressing measurements of free-radical damage than gamma tocopherol and tocotrienols. Lutein ? The carotenoid lutein helps maintain healthy cell division, supports the macula of the eye, and protects the endothelial lining of the arteries.

Boron is an essential nutrient for optimal calcium metabolism and healthy bones and joints. Boron may affect human steroid hormone levels. Dietary boron intake may support a healthy prostate.

The branched chain amino acids (BCAAs) L-valine , L-leucine , and L-isoleucine enhance protein synthesis in liver cells and muscle cells. Because they can be oxidized in the cell?s mitochondria, the branched chain amino acids may also provide energy and may serve as fuel sources for skeletal muscles during periods of metabolic stress. As a result, BCAAs have been used with success to support liver function. A study in 2008 also showed BCAAs supplementation improved insulin resistance and beta cell function as well as energy metabolism and glucose tolerance in certain people. They are also used by athletes. A current mouse study showed restoring hippocampal BCAA concentrations to normal had the effect of reinstating normal brain function by helping the synapses to function efficiently.

Women today face a growing number of health issues, including the need to support DNA gene structure in the breast. Detrimental factors such as the aging process, along with the daily bombardment of damaging environmental estrogen-like compounds, demonstrate the need to support a woman's breast cellular structure. A wealth of research shows that specific plant extracts can positively influence cellular status and help maintain a healthy balance of estrogens. Estrogen is broken down in the body into two important metabolites. Those metabolites are the good 2-hydroxyestroneand the bad 16 alpha-hydroxyestrone. Scientists have identified nutrients like indole-3-carbinol (I3C) that can tip the delicate balance of estrogens in favor of the good form. Women seeking to proactively restore their youthful hormonal balance can now take a phytonutrient-based formula that helps support healthy estrogen activity and detoxification. Some of the active ingredients in the Breast Health Formula are: Phytoestrogens - function as selective estrogen receptor modifiers that help block certain estrogen receptor sites on cells, thus blocking bad estrogen from exerting its harmful effects Plant lignans - boost beneficial enterolactone levels that favorably alter estrogen metabolism Cruciferous vegetable extracts and I3C - effectively increase 2-hydroxyestrone while reducing undesirable 16 alpha-hydroxyestrone Calcium D-glucarate - safely facilitates the removal of harmful estrogen from the body through inhibiting beta-glucuronidase, an enzyme that rips the glucuronide conjugate off the estrogen Vitamin D - restores healthy genetic regulatory switching to aging cells Breast Health Formula provides nutrients that have demonstrated broad-spectrum support for preserving optimal breast health.

As we get older, our eyes become vulnerable to a variety of insults that can cause irritation and dry eye. Applying lubricating eye drops several times a day can alleviate discomfort. The Brite Eyes III formula contains two proven lubricants (hydroxypropylmethylcellulose and glycerin) that are FDA-approved for ophthalmic use without irritation. The Brite Eyes III formula also contains the antioxidant N-acetyl-carnosine, which helps protect the active ingredients against glycation. A box of Brite Eyes III contains two individual vials that hold five milliliters each. This type of packaging in two individual vials reduces the risk of bacterial contamination. And having two vials also makes it convenient for consumers to keep Brite Eyes III readily accessible at home, in the office, purse or pocket ... or anywhere access to soothing eye drops is needed.

Vitamin C, or ascorbic acid, is a white, crystalline, water-soluble substance found in citrus fruits. As an antioxidant, vitamin C scavenges free radicals in the body and protects tissues from oxidative stress. Vitamin C also promotes the absorption of iron, while preventing its oxidation. Vitamin C is a vital cofactor to the formation of collagen, the connective tissue that supports arterial walls, skin, bones, and teeth. More vitamin C is contained in the adrenal glands than any other organ in the body and is required at higher levels during times of stress. Physical stresses on the body such as ingestion of heavy metals, cigarette smoking, immune impairment, extreme temperatures, and chronic use of certain medications such as aspirin also signal the need for increased intake of vitamin C. Along with ascorbic acid, vitamin C also comes in at least two other forms: chemically bonded to minerals as ascorbates, and as the fat-soluble ascorbyl palmitate. Both of these forms are non-acidic. Because humans do not manufacture vitamin C internally, it must be obtained through dietary sources or supplements. Few people realize, however, that vitamin C is a water-soluble nutrient that is quickly oxidized and excreted by the body, which limits its efficacy. Until now, those seeking to capture vitamin C?s optimal health benefits have had no choice but to consume it several times throughout the day. Vitamin C Powder contains four buffering minerals and ascorbic acid. When mixed with water, this product produces a reduced-acid solution that is non-irritating to the stomach and intestinal lining. The minerals also make it a more pleasant-tasting and healthful drink. The substances used in this product make it effervesce for a short while when it is mixed with water.

For nearly three decades, doctors in Germany have used a standardized extract of the herb butterbur for their patients to maintain nasal comfort and head cavity comfort. Butterbur?s main active ingredient is petasin, a phytochemical that may reduce spasms in smooth muscle, thus relaxing swollen nasal membranes. Butterbur Extract with Standardized Rosmarinic Acid contains a patented butterbur extract. State-of-the-art technology allows for standardization of butterbur?s key active ingredients while containing extremely low levels (<0.1 ppm) of Pyrrolizidine alkaloids (PA). This formula also contains standardized rosmarinic acid, a plant polyphenol derived from rosemary leaf. Rosmarinic acid helps to regulate inflammatory responder cells while supporting healthy immune function. Luteolin, another plant flavonoid, has potent fluid-regulating properties both in vitro and in vivo. It also has been shown to help maintain normal respiratory function. Luteolin may also protect against cytokine-induced pancreatic beta-cell damage through suppression of NF-kappaB activation. Also included is perilla leaf extract. When enriched with rosmarinic acid, perilla leaf extract has been shown to provide significant seasonal support for the body.

Calcium is the most abundant mineral in the body ... primarily found in the bones and teeth. In bone formation, calcium forms crystals that provide strength to maturing bone. Peak bone mass is usually achieved when people are in their 20s. Calcium is needed for more than just healthy bones. It is also important for muscle contraction, blood vessel contraction and expansion, the secretion of hormones and enzymes, and sending messages through the nervous system. A meta-analysis of 56 clinical trials demonstrated a significant impact on heart health as a result of increased calcium intake by 1,000 to 2,000 mg/day. In addition, scientific evidence suggests that increased intake of calcium may help to maintain optimal weight as well. Calcium is an essential mineral that is often inadequately supplied, inefficiently absorbed, or excreted faster than it is being assimilated. The citrate salt of calcium has been documented to be well absorbed and utilized by the body. This is the form many doctors and nutritionists recommend. Calcium citrate dissolves easily even if one doesn?t have much stomach acid. Many people naturally produce less acid as they age, so calcium citrate is a good choice for older adults. The addition of vitamin D3 is also critically important because it stimulates calcium absorption and promotes healthy bone density. However, as people age, they often lose the ability to make vitamin D3. Calcium and other minerals are best not taken with fiber, because fiber can interfere with their absorption. There is evidence that calcium from supplements and dairy foods may inhibit iron absorption, although it has been very difficult to distinguish between the effects of calcium on iron absorption versus other inhibitory factors, such as phytate. Calcium supplements are best taken with meals. They should always be taken with a full glass of water, juice, or other liquid to enhance solubility. If calcium-containing formulas are taken only once daily, they may be best taken in the evening.

D-glucarate is found in grapefruit, apples, oranges, broccoli, and Brussels sprouts. D-glucarate supports the body?s cleansing system - a detoxification mechanism called glucuronidation. The human body uses glucuronidation to make a large variety of substances more water-soluble, and, in this way, allow for their subsequent elimination from the body through urine or faeces (via bile from the liver).

The popular Calorie Control Weight Management Formula powder capitalizes on the proven benefits of slowing absorption of carbohydrate calories after each meal and targeting digestive enzymes to support healthy after-meal glucose metabolism. LuraLean propolmannan slows the rapid emptying of ingested food into the small intestine, reducing the surge of glucose entering the bloodstream. It has also been shown to significantly lower after-meal glucose surges.LuraLean binds to bile acids in the small intestine and helps transport them out of the body. These bile acids otherwise facilitate the digestion and assimilation of dietary fat into the bloodstream. And LuraLean works better than other fibers because its enzymes have been removed, sparing it from degradation in the digestive tract. This enables LuraLean to form a stable viscous barrier to help impede calorie absorption and maintain its sponge-like activity throughout the digestive tract. In placebo-controlled studies, LuraLean (propolmannan) induced moderate weight loss of up to 7.92 pounds on average in 8 weeks along with significant reductions in fasting lipid and post-meal glucose/insulin levels.White Kidney Bean extract (Phaseolus vulgaris) inhibits amylase, the digestive enzyme that breaks down carbohydrates to be absorbed into the bloodstream as glucose. Phaseolus vulgaris has produced weight loss of 6.5 pounds on average in 30 days and abdominal fat reductions.Irvingia gabonensis has amylase digestive enzyme inhibiting properties. This African mango extract also favorably regulates Leptin to decrease appetite and facilitate triglyceride removal from adipocytes (fat cells). It also regulates Adiponectin to facilitate insulin sensitivity, and Glycerol-3-phosphate dehydrogenase to inhibit glucose from converting to triglyceride fat in adipocytes. Irvingia has demonstrated weight loss of 20 pounds on average in 10 weeks in placebo-controlled trials.Along with the benefits of Irvingia African Mango extract, a proprietary green tea phytosome enhances the metabolic effects of green tea through better absorption of green tea polyphenols in the blood, including EGCG. It induced 30.1 pounds of weight loss on average in 90 days when combined with a reduced calorie diet.Calorie Control Weight Management Formula is now enhanced with CoffeeGenic Green Coffee Extract. Chlorogenic acid found in green coffee bean extract has been clinically shown to limit dangerous after-meal glucose surges.The new Calorie Control Weight Management Formula has a great new smooth natural blueberry flavor that is much more satisfying to drink than the previous version.