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You save 25%Serving Size 1capAmount per capsule:Pregnenolone 30mgOther Ingredients: Microcrystalline Cellulose, GelatinDirections:Take 1 to 3 caps daily as a dietary supplement.The term ?neurosteroids? applies to those steroids that are both formed and accumulated in the nervous system. Pregnenolone, DHEA, and their sulfates are important brain neurosteroids that are involved in learning and memory, aggression and epilepsy, and modulation of responses to stress, anxiety and depression. Pregnenolone is also a prohormone used by the body to produce other steroid hormones. Before it was pushed aside by the promotion of other hormones, pregnenolone had been shown to have a wide range of beneficial actions for people who were sick or under stress. These included ameliorating arthritis, countering fatigue, and generally improving the quality of life. During the past two decades pregnenolone and its sulfate have been receiving renewed attention. Many scientific studies using mammals and other vertebrates give strong experimental support to claims that pregnenolone can be used to enhance memory and reduce stress. There is also evidence that it lessens depression. Caution: Don?t use pregnenolone if you are at risk for hormonally related cancers, lactating, or pregnant.
You save 25%Serving Size 1capAmount per capsule:Pregnenolone 30mgOther Ingredients: Microcrystalline Cellulose, GelatinDirections:Take 1 to 3 caps daily as a dietary supplement.The term ?neurosteroids? applies to those steroids that are both formed and accumulated in the nervous system. Pregnenolone, DHEA, and their sulfates are important brain neurosteroids that are involved in learning and memory, aggression and epilepsy, and modulation of responses to stress, anxiety and depression. Pregnenolone is also a prohormone used by the body to produce other steroid hormones. Before it was pushed aside by the promotion of other hormones, pregnenolone had been shown to have a wide range of beneficial actions for people who were sick or under stress. These included ameliorating arthritis, countering fatigue, and generally improving the quality of life. During the past two decades pregnenolone and its sulfate have been receiving renewed attention. Many scientific studies using mammals and other vertebrates give strong experimental support to claims that pregnenolone can be used to enhance memory and reduce stress. There is also evidence that it lessens depression. Caution: Don?t use pregnenolone if you are at risk for hormonally related cancers, lactating, or pregnant.
You save 25%Serving Size 1capAmount per capsule:Pregnenolone 50mgOther Ingredients: Microcrystalline Cellulose, GelatinDirections:Take 1 to 3 caps daily as a dietary supplement.The term ?neurosteroids? applies to those steroids that are both formed and accumulated in the nervous system. Pregnenolone, DHEA, and their sulfates are important brain neurosteroids that are involved in learning and memory, aggression and epilepsy, and modulation of responses to stress, anxiety and depression. Pregnenolone is also a prohormone used by the body to produce other steroid hormones. Before it was pushed aside by the promotion of other hormones, pregnenolone had been shown to have a wide range of beneficial actions for people who were sick or under stress. These included ameliorating arthritis, countering fatigue, and generally improving the quality of life. During the past two decades pregnenolone and its sulfate have been receiving renewed attention. Many scientific studies using mammals and other vertebrates give strong experimental support to claims that pregnenolone can be used to enhance memory and reduce stress. There is also evidence that it lessens depression. Caution: Don?t use pregnenolone if you are at risk for hormonally related cancers, lactating, or pregnant.
You save 25%Serving Size 1capAmount per capsule:Pregnenolone 50mgOther Ingredients: Microcrystalline Cellulose, GelatinDirections:Take 1 to 3 caps daily as a dietary supplement.The term ?neurosteroids? applies to those steroids that are both formed and accumulated in the nervous system. Pregnenolone, DHEA, and their sulfates are important brain neurosteroids that are involved in learning and memory, aggression and epilepsy, and modulation of responses to stress, anxiety and depression. Pregnenolone is also a prohormone used by the body to produce other steroid hormones. Before it was pushed aside by the promotion of other hormones, pregnenolone had been shown to have a wide range of beneficial actions for people who were sick or under stress. These included ameliorating arthritis, countering fatigue, and generally improving the quality of life. During the past two decades pregnenolone and its sulfate have been receiving renewed attention. Many scientific studies using mammals and other vertebrates give strong experimental support to claims that pregnenolone can be used to enhance memory and reduce stress. There is also evidence that it lessens depression. Caution: Don?t use pregnenolone if you are at risk for hormonally related cancers, lactating, or pregnant.
About PrimAGE�PrimAGE is a formulation containing two forms of vitamin B-6: pyridoxamine and pyridoxal-5'-phosphate (P5P). (Ordinary vitamin B-6 supplements usually consist of another form, called ?pyridoxine?.) The P5P in our formula slows the body?s conversion of pyridoxamine to other substances, thereby prolonging its activity. What we can?t tell youIn the U.S. and some other industrialized countries, government agencies like the U.S. Food and Drug Administration have adopted censorship as a method for intensifying their control over the supplement industry and its customers. Thus, FDA regulations prohibit us from telling you that any of our products are effective as medical treatments, even if they are, in fact, effective. Accordingly, we will limit our discussion of PrimAGE to a brief summary of recent pyridoxamine research, and let you draw your own conclusions about what medical conditions it may be effective in treating. Protein damage in aging and diabetesWhile it has been known since the 1940s that pyridoxamine is a form of vitamin B-6, it was only recently that its unique and exciting properties came to light.1 In 1996 it was announced that pyridoxamine inhibits the formation of ?Advanced Glycation End-products? (AGEs).2AGEs are damaged proteins ? mainly structural proteins and enzymes ? that have been bonded together by certain sugars in such a way as to impair their normal function. AGEs accumulate in the body as one ages,3 causing tissues to lose their elasticity and causing enzymes to malfunction. In fact, this accumulation of AGEs is considered to be one of the principal causes of aging.4Aging, however, is not the only condition in which AGEs play a major role. Diabetes is another. Periods of high blood sugar (?hyperglycemia?) are a hallmark of diabetes, and the resulting exposure of tissues to certain sugars (especially glucose) greatly increases the rate at which AGEs are formed. The accumulation of AGEs may account for much of the tissue damage that is seen in the diabetic state ? including damage to kidneys (nephropathy), nerves (neuropathy), vasculature (atherosclerosis), and eyes (retinopathy, cataracts).5Pyridoxamine and agingSince aging is not officially recognized as a disease or medical condition by the FDA, we are free to tell you that pyridoxamine looks like an excellent agent for suppressing a major cause of aging. Here is the logic involved: The accumulation of AGEs correlates with aging.3 AGEs cause some of the symptoms of aging, such as tissue stiffness and loss of function.6 Pyridoxamine inhibits the formation of AGEs.7 Therefore, pyridoxamine is likely to suppress some aspects of aging. Only a decades-long clinical study can demonstrate this conclusion beyond a shadow of a doubt, but few would be so foolish as to wait decades for such a study to be completed before going ahead and using pyridoxamine as an anti-aging supplement. Pyridoxamine and diabetic symptomsHere are some highlights of recent research into t
About PriMeric�The main active ingredient in PriMeric is curcumin ? the yellow substance in the turmeric spice. Curcumin has a long history of medicinal use in India and China,1 and in recent years has become a focus of medical research because of its remarkable effects on such processes as tissue damage by free radicals, inflammation, viral replication, and protein handling. Curcumin normally is absorbed poorly from the human digestive tract. Less than 1% of the curcumin one consumes actually makes it into the bloodstream, and the liver rapidly destroys most of this. To eliminate this problem, LifeLink formulated PriMeric with two bioavailability enhancers ? quercetin and piperine ? which not only dramatically increase the absorption but also slow the metabolic conversion of curcumin to inactive substances, giving it a much longer opportunity to act. What we can?t tell youIn the U.S. and some other industrialized countries, government agencies like the U.S. Food and Drug Administration have adopted censorship as a method for intensifying their control over the supplement industry and its customers. Thus, FDA regulations prohibit us from telling you that any of our products are effective as medical treatments, even if they are, in fact, effective. Accordingly, we will limit our discussion of PriMeric to a brief summary of recent curcumin research, and let you draw your own conclusions about what medical conditions it may be effective in treating. Since 1970, when curcumin first attracted the interest of scientific medical researchers, studies of curcumin have reported suppressive effects for the following medical conditions: High serum cholesterol levels2 Free radical damage to tissues1 Diabetic cataracts3 Diabetic damage to pancreatic insulin-producing cells4 Diabetic wounds5 Rheumatoid arthritis6,1 Inflammatory bowel disease, Crohn?s Disease7 Psoriasis8 Cancer9,8,10 Atherosclerosis8,11a,11b Inherited peripheral neuropathies12 Liver damage by chemicals and drugs1 Microbial infections13 Anyone suffering from any of these ailments will probably find encouragement in the fact that medical research has identified curcumin as a possible aid. We want to single out four other medical conditions for which curcumin seems to hold especially exciting prospects: Alzheimer?s Disease Parkinson?s Disease Cystic fibrosis Ailments related to Epstein-Barr Virus Curcumin and Alzheimer?s DiseaseCurcumin has shown pronounced anti-Alzheimer?s effects in animal studies16,17 and is being tested in human clinical trials.16 Its ability to disassemble the brain plaques (amyloid protein) that characterize Alzheimer?s Disease15,17 has led researchers to say that it has the potential both to prevent the condition14,15,17 and to reverse it.15,17Parkinson?s DiseaseAlthough the symptoms of Parkinson?s Disease differ from those of Alzheimer?s Disease, the causes are thought to have much in common. Both diseases involve the formation of protein plaques in the brain,18 the trapp
About Progesterone CreamAs people age, their bodies? hormone production falls. In women, progesterone levels fall far more than do estradiol levels, producing a hormonal state that contributes to such unpleasant problems as PMS, hot flashes, night sweats, osteoporosis, endometriosis, fibrocystic breast disease, anovulation, vaginal dryness, menstrual migraine, depression, and mood swings. Progesterone supplementation is widely used for these conditions as well as for reducing risk of breast cancer during estrogen therapy (as in HRT or breast enhancement). The bioavailability of progesterone is many times greater when applied to the skin (?topically?) than when taken orally. Topical application causes a significant rise in progesterone levels in the blood and other tissues. Penetration efficiency varies from person to person and depends upon where on the body it is applied ? breasts and underarms absorb best. A typical dosage is 1/4 to 1/2 tsp per day, but may need adjustment for optimal results. This product is made from pure crystalline progesterone, identical in molecular structure to the progesterone made by your body.
You save 25%Chinese red yeast Monascus purpureus (grown on white rice, by the way) contains a family of compounds that inhibit HMG-CoA reductase ? an enzyme responsible for making cholesterol in the body. In clinical studies RYR has produced reductions in LDL cholesterol by about 31% and triglycerides by 34%. In animal studies a reduction in atherosclerotic plaques has also been shown.
Life Link's Rhodiola Rosea 250mg 60capRhodiola rosea is a plant native to high-latitude mountains in Europe and Asia. During several decades of research in Russia and Ukraine its constituents and actions have been explored in lab animals and humans. Active compounds identified in Rhodiola species include rhodioniside, rhodiolin, rosin, rosavin, rosarin, and rosiridin. Rhodiola rosea species have been reported to offer generalized resistance against physical, chemical, and biological stressors ? such as exercise, mental work, lack of sleep, and disease. For example, in a study of medical students during an exam period, those who used a Rhodiola extract showed improvements in physical fitness, sleep patterns, mental performance, motivation, and mood. Animal studies have suggested that Rhodiola may have cardioprotective and anticancer effects, as well. (Russian researchers coined the word ?adaptogen? for substances that supposedly have nonspecific anti-stress properties. The term, however, is misleading in that it masks the fact that the substances actually act by quite specific mechanisms that have yet to be understood in detail.) Rhodiola supplementation is also an effective elevator of libido in both sexes, according to psychiatrists at Columbia University.A dose of approximately 120-200 mg daily of a Rhodiola rosea extract standardized for 3% rosavin has been suggested, preferably beginning several weeks prior to a period of stress. Three times that amount is suggested when usage is begun immediately before or during a stressful activity. The dosages required for cognitive or libido enhancement have not been systematically studied, but are probably also in the 100-200 mg range.
Life Link's TMG-15 120CapsTrimethylglycine (TMG), an amino acid found mainly in the liver, plays an important role in protecting the liver, heart, and vasculature. TMG activates an enzyme that neutralizes another amino acid called homocysteine. Chronic elevation of homocysteine is associated with thrombosis (blood clots) and with increased heart and artery disease. TMG has been touted as a treatment for many conditions, including high cholesterol, atherosclerosis, thrombosis, stroke, fatty liver disease, dry mouth, seizures, convulsions, osteoporosis, urinary tract infections, and diseases in general. All of these except the last three are supported by published scientific studies. TMG may also indirectly alleviate certain other problems if, as many believe, it increases the body?s production of S-adenosylmethionine (SAMe). SAMe is said to remyelinate nerves, and ameliorate depression, Alzheimer?s and Parkinson?s diseases. One other interesting characteristic of TMG is that when it acts upon homocysteine or other substrates in the body, it is transformed into DMG (Dimethylglycine), which is used in Russia as an athletic performance enhancer. LifeLink?s TMG is an extract from sugar beets. We have fortified this product with three vitamins that have been shown to improve its effectiveness.
You Save 25%Colloidal trace minerals are mixtures of extremely small crystals of various mineral elements or their salts. Theory holds that particles this size pass easily through cell membranes, making the minerals more available as cofactors for enzymes. Scientific studies are lacking, but many users of these products testify to their effectiveness. LifeLink?s formula contains dozens of minerals, but is particularly rich in potassium, calcium, magnesium, phosphorus, manganese, copper, chromium, zinc and boron
You save 25%Vinpocetine is derived from an alkaloid found in the periwinkle plant. It has become popular as a memory enhancer and cognitive aid and is used to treat a variety of neurological disorders, including: cerebrovascular disorders ? low cerebral blood flow, headache, hypoxia, cerebral atherosclerosis, and stroke; mental impairment ? poor memory, aphasia, motor disorders, senility, and dementias; sensory disorders ? hearing impairment, inner-ear problems, dizziness, low visual acuity, and diabetic retinopathy; failing neuronal metabolism. Most of these uses have clinical and laboratory support.Vinpocetine causes dilation of brain blood vessels and it inhibits blood clotting. These actions improve cerebral blood flow, which might explain many of the neurological benefits. In addition, vinpocetine is thought to increase the absorption of glucose by nerve cells, thereby providing extra energy for the brain. These physiological processes are just beginning to be explored at the molecular level. Since vinpocetine improves memory and cognition in ailing individuals, many perfectly healthy people conclude that it should help them, too ? an idea that makes a lot of sense.
You save 25%Vinpocetine is derived from an alkaloid found in the periwinkle plant. It has become popular as a memory enhancer and cognitive aid and is used to treat a variety of neurological disorders, including: cerebrovascular disorders ? low cerebral blood flow, headache, hypoxia, cerebral atherosclerosis, and stroke; mental impairment ? poor memory, aphasia, motor disorders, senility, and dementias; sensory disorders ? hearing impairment, inner-ear problems, dizziness, low visual acuity, and diabetic retinopathy; failing neuronal metabolism. Most of these uses have clinical and laboratory support.Vinpocetine causes dilation of brain blood vessels and it inhibits blood clotting. These actions improve cerebral blood flow, which might explain many of the neurological benefits. In addition, vinpocetine is thought to increase the absorption of glucose by nerve cells, thereby providing extra energy for the brain. These physiological processes are just beginning to be explored at the molecular level. Since vinpocetine improves memory and cognition in ailing individuals, many perfectly healthy people conclude that it should help them, too ? an idea that makes a lot of sense.
You Save 25% Vitamin C is an essential cofactor for enzymes involved in the synthesis of collagen ? the chief structural protein in muscles, vascular tissues, skin, bones and cartilage. It also plays roles in the synthesis of hormones and neurotransmitters, in immunity, and in prevention of oxidative damage. Major vitamin C deficiency weakens vascular tissue ? a condition called scurvy ? and results in widespread capillary bleeding, bleeding gums, and loosening of the teeth. Lesser deficiencies can be caused by insufficient C intake, physical or psychological stress, smoking, alcohol use, and infections. Symptoms include fatigue, lassitude, loss of appetite, drowsiness, insomnia, irritability, and lowered immunity. Vitamin C has a preventive effect on degenerative processes such as cardiovascular disease and cancer; it speeds wound healing, and prevents carcinogenic nitrosamines from forming in the stomach. In clinical studies, vitamin C supplementation at 1000 mg/day or more has consistently decreased the incidence, symptoms, and duration of colds, and reduced the risk of pneumonia by 80%. In a study of 700 students, Vitamin C (at 1000 mg/hour for the first 6 hours followed by 3000 mg/day) reduced cold and flu symptoms by 85%. ABOUT THE POWDER FORM: A level quarter teaspoon of Vitamin C powder weighs about 1200 mg.ABOUT THE TIME-RELEASE FORM: The body has a limited capacity to absorb vitamin C. The time-release form parcels out the dose, improving absorption and duration of action. Lysine and magnesium are added for synergy in preventing certain conditions such as asthma attacks.
You Save 25% Vitamin C is an essential cofactor for enzymes involved in the synthesis of collagen ? the chief structural protein in muscles, vascular tissues, skin, bones and cartilage. It also plays roles in the synthesis of hormones and neurotransmitters, in immunity, and in prevention of oxidative damage. Major vitamin C deficiency weakens vascular tissue ? a condition called scurvy ? and results in widespread capillary bleeding, bleeding gums, and loosening of the teeth. Lesser deficiencies can be caused by insufficient C intake, physical or psychological stress, smoking, alcohol use, and infections. Symptoms include fatigue, lassitude, loss of appetite, drowsiness, insomnia, irritability, and lowered immunity. Vitamin C has a preventive effect on degenerative processes such as cardiovascular disease and cancer; it speeds wound healing, and prevents carcinogenic nitrosamines from forming in the stomach. In clinical studies, vitamin C supplementation at 1000 mg/day or more has consistently decreased the incidence, symptoms, and duration of colds, and reduced the risk of pneumonia by 80%. In a study of 700 students, Vitamin C (at 1000 mg/hour for the first 6 hours followed by 3000 mg/day) reduced cold and flu symptoms by 85%. ABOUT THE POWDER FORM: A level quarter teaspoon of Vitamin C powder weighs about 1200 mg.ABOUT THE TIME-RELEASE FORM: The body has a limited capacity to absorb vitamin C. The time-release form parcels out the dose, improving absorption and duration of action. Lysine and magnesium are added for synergy in preventing certain conditions such as asthma attacks.
You save 25%Vitamin B-12 is the only vitamin that contains an essential mineral ? cobalt. The term ?Vitamin B-12? was originally applied to cyanocobalamine, but it is now known that this chemical is converted into methylcobalamin and hydroxocobalamin ? the two active forms of the vitamin. LifeLink?s sublingual Xobaline (methylcobalamin) therefore goes into your bloodstream in its active form, eliminating the losses that occur during digestion and liver conversion. Methylcobalamin is an essential cofactor in the enzymatic production of the amino acid methionine from homocysteine. Inadequate B-12 levels can cause or contribute to anemias, fatigue, lethargy, anorexia, developmental delay, homocystinuria, irritability, and poor brain growth. B-12 supplementation produces remarkable effects, even in the absence of a deficiency. High doses promote peripheral nerve regeneration, reduce pain in neuropathies, improve muscle function in ALS, and increase sperm counts; moderate doses can reduce hypersomnia, normalize sleep-wake rhythm, and cure homocysteine-related anemias. Since B-12 and folic acid are both required for the conversion of homocysteine to methionine, LifeLink?s Xobaline contains both of these cofactors.
About Zinc OrotateZinc orotate is a mineral salt that is normally found in the body in small amounts. Each molecule of zinc orotate consists of two molecules of orotic acid and one zinc atom ? the zinc atom replaces a pair of hydrogen atoms (one from each orotic acid molecule). Zinc is an essential element required by all living things. Every organ and tissue in the body contains and requires zinc. It plays roles in development, tissue growth, and in all major bodily functions. Several thousand kinds of proteins in the body contain zinc ? some of these proteins are enzymes that use zinc atoms to catalyze biochemical reactions, others have structural roles. ?Zinc finger? proteins regulate gene expression, and zinc atoms play a role in gene-directed cell death (?apoptosis?) which is a major regulatory process in growth and development, and in cancer and other diseases. Zinc also affects the way cells signal each other ? it has been found to influence hormone release and the transmission of information along nerves.1,2Zinc?s antioxidant properties help to explain some of its effects on the body: protecting the skin from UV light, improving wound healing, and decreasing the relative risk of cancer and cardiovascular disease. Zinc is an essential component of the enzyme superoxide dismutase (SOD) ? one of the major antioxidant tools the body uses to neutralize destructive oxygen ions.3The officially recommended intake of zinc for adult humans is 8 to 11 mg/day.4 Zinc deficiencies occur, even in industrialized countries, as the result of various illnesses and bizarre diets. Symptoms of severe zinc deficiency include: hair loss, skin rashes, diarrhea, impaired immunity and wound healing, night blindness and other visual impairment, loss of smell, taste and memory, wasting of body tissues, behavioral disturbances, and death.1,2Orotate (orotic acid) is a biochemical substance made by all living cells. It is a necessary raw material for making the genetic material: RNA and DNA.5What we can?t tell youIn the U.S. and some other industrialized countries, government agencies like the U.S. Food and Drug Administration have adopted censorship as a method for intensifying their control over supplement users and their suppliers. Thus, FDA regulations prohibit us from telling you that any of our products are effective as medical treatments, even if they are, in fact, effective. Accordingly, we will limit our discussion of zinc orotate to a brief summary of relevant research, and let you draw your own conclusions about what medical conditions it may be effective in treating. Zinc orotate was popularized as a supplement by Dr. Hans Nieper, the innovative German physician,6 who used it to treat or prevent the following conditions:7,8,9cancer Hodgkin and non-Hogkin lymphomas diabetes Nieper considered orotates to be superior to carbonates, chlorides, sulfates, and other anions as bioavailability enhancers for minerals like zinc.8Hans Nieper was a controversial figure w
Ascorbyl palmitate (AP) is a fat-soluble form of Vitamin C. Its antioxidant activity is the same as that of ordinary (water-soluble) Vitamin C, but AP is far more persistent. The palmitate portion of the AP molecule penetrates the membranes of cells and stays there, anchoring the ascorbyl portion just outside the cell membrane, where its antioxidant activitites are most needed. Ordinary Vitamin C molecules, on the other hand, drift around in the watery regions of the body, only occasionally bumping into a cell membrane and doing what we want them to do: quenching free radicals. Medical research indicates that AP stimulates collagen production in skin and other tissues, and that it penetrates into nervous tissue where it protects against free radical damage. Because of its excellent skin penetration and its ability to induce collagen production, ascorbyl palmitate is frequently used in topical formulations of Vitamin C. Studies have shown that it is an effective anti-inflammatory in cases of psoriasis and sunburn, and that it causes skin to become thicker, softer, more resilient, even-toned, and less wrinkled. Both topical and oral formulations have shown powerful anti-tumor actions ? 91% suppression in mouse experiments. When ascorbyl palmitate is swallowed, most of it is broken up into ascorbic acid and palmitic acid during digestion ? only a small portion survives as AP and is absorbed into the body. This low bioavailability is the reason why substantial doses (such as 500 mg) are needed. The bioavailability of AP might be increased by taking it with a teaspoon of baking soda dissolved in water, or by allowing the supplement to dissolve under the tongue ? a possibility that has yet to be investigated. (Users who try this with LifeLink?s product should be aware that the tablets contain some excipients that won?t dissolve.)
About Beta CaroteneBeta-carotene belongs to large group of compounds known as carotenoids that have been widely studied for their protective effects against cancer and heart disease. Beta-carotene is thought to be an antioxidant, but its primary role in nutrition is as a source of vitamin A ? the body converts beta-carotene into vitamin A as needed. Many studies have shown that beta-carotene supplementation can prevent or inhibit various cancers ? such as cancers of lung, skin, colon, stomach, and liver. But recent studies have also shown that nicotine and heavy alcohol usage can reverse this effect. A similar phenomenon has been seen in heart disease ? beta-carotene is protective except in smokers and drinkers, where it becomes a liability. On the other hand, beta-carotene supplementation (at 50 mg on alternate days) has been shown to reduce the risk of cataracts among smokers by about 25%. Among non-smokers, beta-carotene showed no cataract inhibition, but appeared to reduce the risk of advanced Age-related Macular Degeneration by about 25%. Beta-carotene is also used routinely to treat certain photosensitivity diseases. Generally speaking, the effectiveness of beta-carotene is enhanced when it is combined with other carotenoids, such as lycopene and lutein. The bioavailability of oral beta-carotene supplements is very low but can be increased about 60% by adding a piperine supplement (such as Bioperine�) at 5 mg/day. Animal experiments suggest that a zinc supplement might act similarly.
About Bioperine�Bioperine is a standardized extract from the fruits of black pepper (Piper nigrum) or long pepper (Piper longum). Its piperine content is 95% or more, compared to only 3-9% found in raw forms of these peppers. Black pepper extract has been used extensively in Ayurvedic medicine to treat fevers, digestive disorders, urinary difficulties; rheumatism, neuralgia, and boils. Recent scientific studies have shown that piperine can greatly increase the bioavailability of many other compounds ? such as vitamins, minerals, drugs, and herbal substances. For example, in humans the bioavailability of curcumin was increased by a factor of 20 when used with piperine. Piperine improves the absorption of these compounds in the intestine, promotes their retention in cells, and prevents their being metabolized in the liver. Piperine has also shown promise as an agent for preventing diarrhea, gastric ulcers, stimulating digestive enzymes, suppressing the induction and spread of lung cancer, preventing epileptic convulsions, and stimulating melanin production. This supplement is usually used at 5-10 mg/dose. It is rapidly absorbed and its effects on bioavailability of other compounds lasts 1-2 hours. Doses higher than 10 mg require careful consideration of potential drug interactions.
About Broccoli Sprouts ExtractBroccoli (Brassica oleracea) contains relatively high concentrations of sulforaphane ? a naturally-occurring chemical that reduces the risk of developing cancer. It appears that sulforaphane mobilizes a set of enzymes that neutralize highly reactive cancer-causing chemicals before they can damage DNA and promote cancer. When rats were fed broccoli sprout extracts and then exposed to the powerful carcinogen dimethylbenzanthracene, they developed fewer tumors than rats not fed the extracts; and those tumors that did grow on treated rats were smaller and developed more slowly. One tablet of our broccoli sprouts extract provides the equivalent of 128 grams (4.5 ounces) of fresh broccoli.
About CarnosineCarnosine consists of the amino acids beta-alanine and L-histidine chemically bound to each other. Nerve and muscle cells contain high levels of carnosine. Carnosine is thought to be an antioxidant that quenches several of the most destructive free radicals. This alone would qualify it as an inhibitor of aging and the age-related ailments. Carnosine also regulates zinc and copper concentrations in nerve cells, helping to prevent overstimulation by these neuroactive minerals. These antioxidative and regulatory properties may explain some of the benefits typically claimed for carnosine as a supplement. For example, it is said that carnosine: rejuvenates cells approaching senescence rejuvenates connective tissue cells, improving wound healing when used in eye drops, delays vision senescence, including that caused by cataracts protects the brain against protein cross-linking, glycation, excitotoxicity and oxidation inhibits plaque formation in the brain?s microvasculature, thus reducing risk of senility or Alzheimer?s disease protects nerves from damage by methamphetamine enables the heart to contract more efficiently protects DNA from oxidative damage inhibits skin collagen cross-linking, improving elasticity and reducing wrinkles inhibits free radical damage to blood proteins; reduces the damage normally cause by ischemic stroke increases the average life span of animals What we know about carnosine?s biological role makes the above claims plausible, even where scientific evaluation is lacking. Other claimed benefits from carnosine supplementation would require different explanations. These include: reduces autism symptoms (confirmed in a recent clinical trial) improves strength in high-intensity exercise (suggested by a recent clinical trial) lowers blood pressure improves immune function has anti-cancer effects reduces incidence of peptic ulcers converts body fat into energy ameliorates congestive heart failure The suggested dose is one 500 mg capsule, 2 or 3 times per day. Small doses (such as 50 mg) are probably useless.
About Cat?s ClawCat?s Claw is made from the inner bark of the woody vine Uncaria tomentosa from the Amazon rainforest. It has been used by Peruvian tribes for at least 2000 years to treat a wide variety of ailments including many inflammatory conditions, infections, ulcers, and certain cancers. Recent scientific studies of Cat?s Claw have confirmed its usefulness in all of these areas. It is now employed as an immune stimulator, and as a treatment for inflammatory conditions such as arthritis and ulcers. In clinical trials it has shown benefit in reducing symptoms of osteo- and rheumatoic arthritis. Other studies suggest an ability to suppress breast cancer proliferation, protect DNA from chemical-induced damage, and to increase longevity of immune cells. Cat?s Claw also contains alkaloids with properties that suggest its use for cardiovascular conditions, for prevention of blood clots and strokes, for slowing the heart rate and for lowering blood cholesterol.
ChoLESStat is a mixture of six different kinds of cholesterol-controlling agents:Niacin ? a B-vitamin (B-3) with a substantial history of use for preventing atherosclerosis. Studies have shown that niacin lowers LDL (?bad?) cholesterol and is particularly good at raising HDL (?good?) cholesterol. Flavonoids and other polyphenols (from citrus and olives) ? shown in clinical trials to improve HDL-to-LDL cholesterol ratios Guggul extract ? from resin of the Commiphora mukul tree. In clinical trials guggul extracts lowered LDL levels and triglycerides. Beta-sitosterol and other phytosterols ? plant-derived steroidal substances with chemical structures similar to that of cholesterol. Phytosterols can block absorption of cholesterol from the digestive tract, thereby lowering their levels in the blood. Inositol Hexanicotinate ? a good cholesterol-lowering compound used prior to the 1980s when it was eclipsed by more expensive treatments Policosanol ? a mixture of alcohols from sugar cane wax that in clinical trials showed cholesterol-regulating properties comparable to statin drugs (such as Lipitor�). Each of the components of ChoLESSstat have shown substantial cholesterol-improving properties in clinical trials, and some of them outperformed the latest prescription drugs in both efficacy and safety. Since their mechanisms of action differ from one another, they are expected to work together synergistically to achieve an even better cholesterol profile. The suggested dose is two capsules per day.
Chromium picolinate consists of the element chromium bound to picolinic acid (a substance normally found in the body). The picolinate form of chromium is believed to be considerably more bioavailable than other chromium compounds ? and picolinic acid happens to have cancer-preventing properties of its own. Chromium is an essential trace mineral involved in glucose metabolism, regulation of insulin levels, and maintenance of healthy blood levels of cholesterol and other lipids. In the body chromium is transformed into its biologically active form, known as glucose tolerance factor, in which it is complexed with nicotinic acid. This complex facilitates the interaction of insulin with its receptor. Dietary chromium intake in the developed countries is said to be roughly half of the generally accepted minimum (50 micrograms). Insufficient dietary chromium is associated with maturity-onset diabetes and with cardiovascular diseases. Chromium picolinate supplements have been widely promoted as agents for producing significant and long-term weight loss, metabolic rate increases, appetite control, lowered serum cholesterol, blood sugar regulation, increased energy and stamina, reduced body fat, larger muscles, and for treatment and prevention of diabetes and alcoholism. The claims made for these uses are mostly extrapolations from biochemical experiments and animal studies, and many may turn out to be exaggerations. Nevertheless, animal studies have shown that high doses of chromium do produce increased lean body mass, decreased fat mass, decreased growth of tumors, improved insulin activity, and increased life spans ? and it is reasonable to think that chromium has similar effects in humans. Pronunciation: picolinate (PEEK-oh-leen-ate)
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