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L-Carnitine is an amino acid found in high concentrations in heart and liver tissue where it participates in metabolizing fatty acids into energy in the mitochondria. L-Carnitine also facilitates the metabolism of carbohydrates and enhances the rate of oxidative phosphorylation.L-Carnitine works synergistically with Co-Q10 an antioxidant and energy co-factor that is found in the inner membrane of the mitochondria. Biosint? L-Carnitine is manufactured by Sigma-Tau Industries S.p.A. (Rome Italy) the pioneer in L-Carnitine science.DuraCarn? L-Carnitine Fumarate is a superior stable form of L-Carnitine and is 58% elemental carnitine. 862 mg of L-Carnitine Fumarate yields 500 mg elemental L-Carnitine.