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Bromelain, a mixture of proteases extracted from the stem of the pineapple, has been used by Europeans for many years to inhibit inflammatory factors. Bromelain?s fluid-regulating properties may result from its ability to effectively suppress inflammatory cytokine production, inhibit neutrophil migration, and support removal of some cell surface inflammatory molecules. Research also shows that bromelain may help support healthy blood viscosity and blood platelet aggregation. Bromelain has to be enteric coated so that it will not be activated in the stomach and used as a digestive enzyme. Enteric-coated bromelain tablets pass into the small intestine where they are absorbed into the bloodstream to provide systemic benefits. Specially coated bromelain may significantly modulate inflammatory reactions in the joints. Research has demonstrated that enteric-coated bromelain formulations are at least as effective as other approaches in supporting joint comfort, function and health and are well tolerated. One study even found that bromelain is more effective than other methods for maintaining joint function at rest (41% for bromelain versus 23% for other methods). Another study showed that specially coated bromelain yielded an overall improvement in general well-being, along with improvement in comfort and physical function.

Although biochemistry is a big factor, we?re also affected by what happens to us in our lives. We?re all hit by unpleasant events that may cause brain levels of norepinephrine and dopamine to fall temporarily. People with naturally large reserves usually get through the troubling times with minimal difficulties, but those with initially low chemical levels are more likely to be affected. St. John?s Wort ( Hypericum perforatum extract) is a weak inhibitor of monoamine oxidase (MAO), which destroys monoamine neurotransmitters including dopamine in the brain and leads to low spirits. St. John?s Wort has also been shown to inhibit re-uptake of several neurotransmitters, such as serotonin, dopamine, noradrenaline, and GABA in the brain, and to reduce expression of interleukin-6. Each of these actions can contribute to alleviating low mood status by slowing the recycling of neurotransmitters needed for maintaining emotional balance. Flavonoids, hypericin and pseudo-hypericin, are the constituents thought to be associated with the benefits of St. John?s Wort. In particular, hypericin appears to be the active ingredient.

Strontium has been prescribed in Europe for years to promote healthy bone aging. Strontium is a trace mineral whose metabolism is closely linked to that of calcium. (It resembles calcium at the molecular level.) Strontium concentrates in the skeletal system, where it plays a key role in supporting bone tissue density. The suggested daily serving of 3 vegetarian Strontium Caps supplies 750 mg of this vital trace mineral.

Alpha-lipoic acid is an antioxidant used in Europe to promote liver and nerve health, and confer protective benefits against oxidative processes. Alpha-lipoic acid has been called the "universal" antioxidant because it boosts glutathione levels in cells already within a normal range and has potent antioxidant actions. Research has strongly implicated cellular oxidative damage caused by free radicals as a cause of many problems. What makes alpha-lipoic acid so effective as an antioxidant is its ability to quench free radicals in both aqueous and lipid environments. This means that the antioxidant activity of alpha-lipoic acid is working in the extra-cellular fluid and also within the cell. It also has metal chelating ability, helping the body rid itself of accumulated ingested toxins. Alpha-lipoic acid also is a cofactor for some of the key enzymes (alpha keto acid dehydrogenases) involved in generating energy from food and oxygen in mitochondria and thus plays a critical role in energy production within the cell's mitochondria. One of the most beneficial effects of alpha-lipoic acid is its ability to regenerate other essential antioxidants such as vitamins C and E, coenzyme Q10, and glutathione, and the activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx). The evidence is especially strong for the ability of DHLA (dihydrolipoic acid, a reduced form of alpha-lipoic acid) to recycle vitamin E. This is apparently achieved directly by quenching tocopherol radicals or indirectly by reducing vitamin C or increasing the levels of ubiquinol (a derivative of CoQ10) and glutathione, that, in turn, helps regenerate tissue levels of vitamin E. In clinical studies to date with alpha-lipoic acid, there have been no reported serious adverse side effects, even at high doses. Among the mild, reversible side effects found in some patients have been allergic skin reactions and possible hypoglycemia in diabetics. Please note that the R-lipoic acid (see product in this section) provides a more biologically active form of lipoic acid than alpha-lipoic acid at only a slightly higher cost.

Curcumin is impressing scientists around the world with its remarkable multiple health benefits. Curcumin is a polyphenol present in the spice turmeric and was first used by Indians over 3,000 years ago in traditional Ayurvedic medicine. Modern science has found that curcumin has remarkable antioxidative, immunomodulatory, proapoptotic, hepatoprotective and antiangiogenic properties. Curcumin is also found to increase detoxifying enzymes and promote healthy DNA function. Studies have tied inflammation to overexpression of a protein molecule called nuclear factor-kappa B (NF-kappaB). NF-kappaB acts like a switch to turn on genes that produce the body?s inflammatory responses. Because NF-kappaB?s expression increases in aging adults, scientists have sought ways to modulate NF-kappaB and its effects in the body. Curcumin has been shown to exert powerful inhibitory effects on NF-kappaB activation within the body.138-141 Curcumin inhibits overexpression of NF-kappaB. In addition, curcumin inhibits the metabolism of arachidonic acid, as well as activities of cyclooxygenase, lipoxygenase, and cytokines (interleukins and tumor necrosis factor). Other clinical trials suggest roles for curcumin in helping maintain healthy bowel and joint functions. Curcumin can also help maintain normal healthy platelet function, and have immunomodulatory effects by inhibiting histamine release from mast cells. Other studies show curcumin?s potential for supporting healthy brain function and offering neuroprotection.Curcumin may effectively support pancreatic islet health. Curcumin?s multifaceted effects include protecting against estrogen-mimicking chemicals, protecting against free radicals, and promoting normal cell cycle growth. The problem is that curcumin is poorly absorbed into the bloodstream. Super Bio-Curcumin absorbs up to seven times better than conventional curcumin. So this patented formula represents the most cost-effective way to supplement with this critical nutrient. Studies show that one 400 mg capsule a day of this turmeric compound can provide curcumin blood levels equal to ingesting 2,500-2,800 mg of commercial curcumin supplements. And not only does this turmeric formulation provide far greater peak blood levels, but the curcumin remains in the bloodstream almost twice as long as conventional supplements. And this enhanced absorption delivery complex provides other beneficial turmeric compounds in addition to standardized curcumin. Each 400 mg capsule of Super Bio-Curcumin is equivalent to 2,772 mg of a typical 95% curcumin extract.

Despite incredible scientific validation, many people still do not take vital life-sustaining nutrients because they don't want to swallow so many pills. This problem has been solved with a one-per-day softgel that includes more health-promoting nutrients than any other supplement. The Life Extension Super Booster contains optimal amounts of critical oil-based nutrients and is designed to complement the Life Extension Mix. The Super Booster provides high doses of the most effective form of vitamin K known as menaquinone-7. Just one Super Booster softgel provides: Gamma Tocopherol - If one consumes only alpha tocopherol, the critically important gamma tocopherol is displaced from cells within the body.115 While alpha tocopherol vitamin E suppresses lipid peroxidation, the gamma tocopherol form quenches the dangerous peroxynitrite free radical. It is especially important for those who take vitamin E supplements to make sure they consume at least 200 mg of gamma tocopherol daily. Sesame Lignans - Sesame lignans augment the antioxidant effects of both alpha and gamma tocopherol. In a human study, gamma tocopherol plus sesame lignans were 25% more effective in suppressing measurements of free-radical damage than gamma tocopherol and tocotrienols. Vitamin K - Vitamin K1 from dietary plant sources is poorly absorbed and only a small fraction gets into the bloodstream. Vitamin K2 is absorbed much more efficiently. Scientific studies show K2 provides superior benefits for the bones, arteries, and other tissues. The MK-4 form of vitamin K2 is the most rapidly absorbed and is now routinely used in Japan to maintain healthy bone density. MK-4, however, only remains active in the blood for a few hours. The MK-7 form of K2, on the other hand, remains bioavailable to the human body over a sustained 24-hour period. Super Booster now provides a potent dose of MK-7 to keep calcium in the bone and out of the arteries, along with MK-4 and vitamin K1. Lycopene - Evidence suggests that people who ingest the carotenoid lycopene enjoy healthier prostate function. Lycopene also helps guard against LDL oxidation. Lutein - The carotenoid lutein helps maintain healthy cell division, supports the macula of the eye, and protects the endothelial lining of the arteries. Ginkgo - Hundreds of studies indicate the multifaceted effects of Ginkgo biloba in promoting healthy circulatory and neurological function. Chlorophyllin - Scientific studies indicate that chlorophyllin may be the most potent nutrient to protect against environmentally induced damage to DNA. The Super Booster saves consumers huge dollars by combining a wide variety of costly nutrients into one daily capsule. If you add up the price of the individual ingredients contained in the Super Booster, you would spend two to three times more for this potency if taken separately.

Carnosine is a multifunctional dipeptide made up of a chemical combination of the amino acids beta-alanine and L-histidine. It is found both in food and in the human body. Long-lived cells such as nerve cells (neurons) and muscle cells (myocytes) contain high levels of carnosine. Muscle levels of carnosine correlate with the maximum life spans of animals. Carnosine is a naturally occurring antioxidant that has been shown to be an anti-glycating agent.This nutrient also has the ability to suppress formation of advanced glycation end products (AGEs) and reactive oxygen species (ROS), culprits in metabolic dysfunction and oxidative stress that can lead to age-related conditions. Carnosine levels decline with age. Muscle levels decline 63% from age 10 to age 70, which may account for the normal age-related decline in muscle mass and function.Since carnosine acts as a pH buffer, it can keep on protecting muscle cell membranes from oxidation under the acidic conditions of muscular exertion. Carnosine enables the heart muscle to contract more efficiently through enhancement of calcium response in heart myocytes.Aging causes irreversible damage to the body?s proteins. One underlying mechanism behind this damage is glycation. Glycation involves the non-enzyme controlled cross-linking of proteins and sugars to form non-functioning structures in the body. The process of glycation can be superficially seen as unsightly wrinkled skin. Glycation is also an underlying cause of age-related neurologic, vascular, and eye problems. Carnosine is a unique dipeptide that can interfere with the glycation process.Benfotiamine, a derivative of thiamine (vitamin B1), provides additional protection against glycation reactions while guarding cells against the toxic effects of chronic glucose exposure. Even people with normal glucose levels encounter damaging sugar reactions over a lifetime. Benfotiamine protects against glucose-induced cell damage via several mechanisms.

Carnosine is a multifunctional dipeptide made up of the amino acids beta-alanine and L-histidine. It is found both in food and in the human body. Long-lived cells such as nerve cells (neurons) and muscle cells (myocytes) contain high levels of carnosine. Muscle levels of carnosine correlate with the maximum life spans of animals. Carnosine has a number of antioxidant properties and has been shown to be an anti-glycating agent. This nutrient has the ability to suppress formation of advanced glycation end products (AGEs) and inhibit the formation of reactive oxygen species (ROS) , a culprit in oxidative stress that can lead to age-related conditions. Carnosine levels decline with age. Muscle levels decline 63% from age 10 to age 70, which may account for the normal age-related decline in muscle mass and function. Since carnosine acts as a pH buffer, it can keep on protecting muscle cell membranes from oxidation under the acidic conditions of muscular exertion. Carnosine enables the heart muscle to contract more efficiently through enhancement of calcium response in heart myocytes. Aging causes irreversible damage to the body?s proteins. One underlying mechanism behind this damage is glycation. Glycation involves the non-enzyme controlled cross-linking of proteins or lipids and sugars to form non-functioning structures in the body. The process of glycation can be superficially seen as unsightly wrinkled skin. Glycation is also an underlying cause of age-related neurologic, vascular, and eye problems. Carnosine is a unique dipeptide that can interfere with the glycation process. Benfotiamine, a derivative of thiamine (vitamin B1), provides additional protection against glycation reactions while guarding cells. Even people with normal glucose levels encounter damaging sugar reactions over a lifetime. Benfotiamine protects against glucose-induced cell damage via several mechanisms.

Conjugated linoleic acid (CLA) refers to a group of positional and geometric isomers of linoleic acid, which are found primarily in meat and dairy products. CLA has been shown in a number of studies to have a wide variety of benefits with regards to the immune system, cardiovascular protection, blood sugar maintenance, lipid profiles and body composition. In studies that support the use of CLA in a weight loss program, the amount of CLA used varies from 1.7 to 12 grams per day. Those studies included: A study that showed a dose of 3.4 g CLA per day for 12 weeks seems to be sufficient to reduce body fat mass (BFM) significantly in overweight and obese humans. Another study on human subjects that showed 3.2 g per day of CLA increased lean body mass over a 12 week peri-od. A six-month study on healthy or overweight adults showed CLA decreased body fat mass in specific regions of the body for all participants. Another six-month study on healthy overweight people showed that supplementation with CLA prevented weight gain dur-ing the holiday season. Modest loss in fat mass has been shown using 3.2 grams per day of CLA. Sesame lignans have been shown to stimulate fatty acid oxidation in the liver, and help stimulate lipolysis (fat breakdown). This CLA formulation contains guarana with caffeine. Those who are hypersensitive to caffeine should take CLA without guarana.

Conjugated linoleic acid (CLA) refers to a group of positional and geometric isomers of linoleic acid, which are found primarily in meat and dairy products. CLA has been shown in a number of studies to have a wide variety of benefits with regards to the immune system, cardiovascular protection, blood sugar maintenance, lipid profiles and body composition. In studies that support the use of CLA in a weight loss program, the amount of CLA used varies from 1.7 to 12 grams per day. Those studies included: A study that showed a dose of 3.4 g CLA per day for 12 weeks seems to be sufficient to reduce body fat mass (BFM) significantly in overweight and obese humans. Another study on human subjects that showed 3.2 g per day of CLA increased lean body mass over a 12 week period. A six-month study on healthy or overweight adults showed CLA decreased body fat mass in specific regions of the body for all participants. Another six-month study on healthy overweight people showed that supplementation with CLA prevented weight gain during the holiday season. Modest loss in fat mass has been shown using 3.2 grams per day of CLA. Sesame lignans have been shown to stimulate fatty acid oxidation in the liver, and help stimulate lipolysis (fat breakdown).

Ginkgo biloba is one of the oldest trees known and has been used to support health for nearly 2,800 years. Ginkgo has been found to: Support healthy circulation Help maintain the normal function and tone of blood vessels Support healthy oxygen and glucose metabolism in the brain Stabilize capillaries and make them less fragile Support normal coagulation of blood Support healthy aging in the brain Ginkgo leaf extracts contain several active constituents with neuroprotective and cardioprotective properties. These include flavonoids (e.g., rutin, quercetin, kaempferol, and proanthocyanidins), terpenoids (i.e., ginkgolides), and organic acids. Flavonoids are known to strengthen capillaries, promote healthy blood flow to the brain, and help maintain cognitive health. In a study to determine whether ginkgo extract could prevent age-associated cellular changes, the brain and liver mitochondria of old mice fed ginkgo extract in their drinking water was compared to those of young and old control mice. Mitochondria from the mice given ginkgo exhibited significantly less genetic damage, peroxide generation, and oxidation of the crucial antioxidant glutathione than non-supplemented mice. In addition, mitochondria from old mice given the ginkgo extract resembled those of young mice much more closely, being similar in size and morphology. The study concluded that standardized ginkgo extract prevents age-related decline in mitochondrial structure and function by protecting mitochondria from oxidative damage. Flavonoids such as quercetin and kaempferol from Ginkgo biloba are potent antioxidants and scavengers of many species of free radical, protecting against oxidative cell damage. Ginkgo protects the energy-producing mitochondria in the cells, thus enhancing oxygen utilization and cellular respiration. Ginkgo may also inhibit production of pro-inflammatory cytokines IL-1beta and TNF-alpha while upregulating the production of an anti-inflammatory cytokine called IL-10. The premium-quality biochemical extract in Super Ginkgo Extract 28/7 has been concentrated and dual-standardized to ensure the highest quality, consistency and biological activity.

There are three forms of vitamin K that the human body can utilize to promote arterial health and bone support. Life Extension?s Super K with Advanced K2 Complex provides the dynamic trio of vitamin K forms in one softgel, including vitamin K1, vitamin K2 (MK-4), and vitamin K2 (MK-7). Vitamin K1 is the form of vitamin K that is found in green vegetables. K1 is tightly bound to plant fiber, so only a fraction is absorbed into the bloodstream. Supplementation ensures ample K1 blood levels. Vitamin K2 is usually found in meats, dairy, and egg yolks. Since you may be avoiding these foods for health reasons, ingesting a K2 supplement is essential. MK-4 is the most rapidly absorbed form of K2, and MK-7 boasts a very long half-life in the body, making both forms the perfect complement to any vitamin K regimen.

Low levels of testosterone have been implicated in a host of life-threatening health problems. Maintaining normal testosterone levels is one of the most important steps men can take to regain their health and improve their performance. If you?re over 40, odds are you?re already starting to feel the debilitating effects of low testosterone. Research shows that by age 60, men typically produce 60% less testosterone than they did at age 20. With this drastic reduction comes several well documented problems - from the blues and cognitive decline to reduced sex drive and abdominal fat gain. Normal testosterone has been associated with maintaining a healthy cardiovascular system. Super MiraForte contains high potencies of chrysin and nettle root extract. These ingredients reduce the aromatization (conversion) of testosterone to estrogen and enhance free testosterone levels. Bioperine is included to facilitate the absorption of chrysin (a flavonoid) into the bloodstream. Muira puama is a rainforest herb classified in the Brazilian Pharmacopoeia as an aphrodisiac. In a trial of men with decreased libido and other sexual issues, 62% of those taking muira puama reported positive results in regard to libido, while 51% of those with a common sexual problem felt that the herb was helpful.5 A second trial examined men with decreased libido and found that 85% of the test subjects taking muira puama enjoyed an enhanced libido, 90% had improved sexual function, and 100% of test subjects experienced an increase in intercourse frequency. To augment these protective effects, a standardized lignan extract from Norwegian spruce has been added to Super MiraForte. These lignans convert to enterolactone in the intestine. They are then rapidly absorbed into the bloodstream where they provide significant biological effects. Enterolactone has demonstrated antiestrogen and anti-DHT effects that are of particular importance for the aging prostate gland.

The body needs fatty acids to survive and is able to make all but two of them: linoleic acid (LA) , in the omega-6 family, and alpha-linolenic acid (ALA) in the omega-3 family. These two fatty acids must be supplied by the diet and are therefore considered essential fatty acids (EFAs). Omega-3 fatty acids , found in coldwater fish (and fish oil), perilla and flaxseed oils, are essential elements of a healthy diet. Omega-3 oils contain eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are usually lacking in the typical Western diet, which is filled with foods containing high amounts of omega-6 fats. EPA and DHA can be synthesized in the body from ALA, but EPA and DHA synthesis may be insufficient under certain conditions and for most people that consume Western diets. Studies associate the Mediterranean diet - rich in omega-3 fatty acids, monounsaturated fatty acids such as that found in olive oil, and antioxidant-rich fruits, vegetables, and herbs - with lowered cardiovascular risk and increased life span. Other studies support omega-3?s importance in cardiovascular health. Life Extension?s Super Omega-3 is a premium, scientifically-validated fish oil concentrate, derived from sustainable sources, that contains a proprietary, full-spectrum blend of synergistic nutrients to provide scientifically-validated cardioprotective health benefits. An abundance of scientific research substantiates the wide-ranging health benefits of omega-3 fatty acids in fish oil and monounsaturated fatty acid and polyphenols in olive fruit. No other commercially available fish oil supplement contains this level of essential fatty acids, sesame lignans and olive fruit polyphenols. Super Omega-3 from Life Extension uses a proprietary EPA/DHA technology that results in a pure, stable and easy-to-tolerate fish oil extract . The Pure+ fish oil used in Super Omega-3 is produced with a proprietary technology that purifies the oil with a highly advanced distillation process to reduce environmental pollutants to extremely low levels. The result is an improved fish oil that exceeds the standards set by international rating agencies. The unstable nature of fatty acids like fish oil limits their biological efficacy in the body. Scientific studies show that when sesame lignans are supplemented with fish oil, the beneficial effects are augmented. Sesame lignans help guard against lipid peroxidation , thereby extending the stability of DHA in the body. These lignans also direct fatty acids toward pathways which can help with inflammatory reactions. Super Omega-3 provides standardized sesame lignans to enhance the overall benefits of the improved EPA/DHA fish oil blend. To emulate a Mediterranean diet, Super Omega-3 provides a standardized olive fruit extract to deliver the polyphenol hydroxytyrosol , a powerful antioxidant that protects normal LDL from oxidation and counters dangerous free radicals. Research shows that a combination of olive oil and fish oil supplements

The body needs fatty acids to survive and is able to make all but two of them: linoleic acid (LA) , in the omega-6 family, and alpha-linolenic acid (ALA) in the omega-3 family. These two fatty acids must be supplied by the diet and are therefore considered essential fatty acids (EFAs). Omega-3 fatty acids , found in coldwater fish (and fish oil), perilla and flaxseed oils, are essential elements of a healthy diet. Omega-3 oils contain eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are usually lacking in the typical Western diet, which is filled with foods containing high amounts of omega-6 fats. EPA and DHA can be synthesized in the body from ALA, but EPA and DHA synthesis may be insufficient under certain conditions and for most people that consume Western diets. Studies associate the Mediterranean diet - rich in omega-3 fatty acids, monounsaturated fatty acids such as that found in olive oil, and antioxidant-rich fruits, vegetables, and herbs - with lowered cardiovascular risk and increased life span. Other studies support omega-3?s importance in cardiovascular health. Life Extension?s Super Omega-3 is a premium, scientifically-validated fish oil concentrate, derived from sustainable sources, that contains a proprietary, full-spectrum blend of synergistic nutrients to provide scientifically-validated cardioprotective health benefits. An abundance of scientific research substantiates the wide-ranging health benefits of omega-3 fatty acids in fish oil and monounsaturated fatty acid and polyphe-nols in olive fruit. No other commercially available fish oil supplement contains this level of essential fatty acids, sesame lignans and olive fruit polyphenols. Super Omega-3 from Life Extension uses a proprietary EPA/DHA technology that results in a pure, stable and easy-to-tolerate fish oil extract . The Pure+ fish oil used in Super Omega-3 is produced with a proprietary technology that purifies the oil with a highly advanced distillation process to reduce environmental pollutants to extremely low levels. The result is an improved fish oil that exceeds the standards set by international rating agencies. The unstable nature of fatty acids like fish oil limits their biological efficacy in the body. Scientific studies show that when sesame lignans are supplemented with fish oil, the beneficial effects are augmented. Sesame lignans help guard against lipid peroxidation , thereby extending the stability of DHA in the body. These lignans also direct fatty acids toward pathways which can help with inflammatory reactions. Super Omega-3 provides standardized sesame lignans to enhance the overall benefits of the improved EPA/DHA fish oil blend. To emulate a Mediterranean diet, Super Omega-3 provides a standardized olive fruit extract to deliver the polyphenol hydroxytyrosol , a powerful antioxidant that protects normal LDL from oxidation and counters dangerous free radicals. Research shows that a combination of olive oil and fish oil supplement

The body needs fatty acids to survive and is able to make all but two of them: linoleic acid (LA) , in the omega-6 family, and alpha-linolenic acid (ALA) in the omega-3 family. These two fatty acids must be supplied by the diet and are therefore considered essential fatty acids (EFAs). Omega-3 fatty acids , found in coldwater fish (and fish oil), perilla and flaxseed oils, are essential elements of a healthy diet. Omega-3 oils contain eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are usually lacking in the typical Western diet, which is filled with foods containing high amounts of omega-6 fats. EPA and DHA can be synthesized in the body from ALA, but EPA and DHA synthesis may be insufficient under certain conditions and for most people that consume Western diets. Studies associate the Mediterranean diet - rich in omega-3 fatty acids, monounsaturated fatty acids such as that found in olive oil, and antioxidant-rich fruits, vegetables, and herbs - with cardiovascular health and increased life span. Other studies support omega-3?s importance in cardiovascular health. Life Extension?s Super Omega-3 is a premium, scientifically-validated fish oil concentrate, derived from sustainable sources, that contains a proprietary, full-spectrum blend of synergistic nutrients to provide scientifically-validated cardioprotective health benefits. An abundance of scientific research substantiates the wide-ranging health benefits of omega-3 fatty acids in fish oil and monounsaturated fatty acid and polyphenols in olive fruit. No other commercially available fish oil supplement contains this level of essential fatty acids, sesame lignans and olive fruit polyphenols. Super Omega-3 from Life Extension uses a proprietary EPA/DHA technology that results in a pure, stable and easy-to-tolerate fish oil extract . The Pure+ fish oil used in Super Omega-3 is produced with a proprietary technology that purifies the oil with a highly advanced distillation process to reduce environmental pollutants to extremely low levels. The result is an improved fish oil that exceeds the standards set by international rating agencies. The unstable nature of fatty acids like fish oil limits their biological efficacy in the body. Scientific studies show that when sesame lignans are supplemented with fish oil, the beneficial effects are augmented. Sesame lignans help guard against lipid peroxidation , thereby extending the stability of DHA in the body. These lignans also direct fatty acids toward pathways which can help with inflammatory reactions. Super Omega-3 provides standardized sesame lignans to enhance the overall benefits of the improved EPA/DHA fish oil blend. To emulate a Mediterranean diet, Super Omega-3 provides a standardized olive fruit extract to deliver the polyphenol hydroxytyrosol , a powerful antioxidant that protects normal LDL from oxidation and counters free radicals. Research shows that a combination of olive oil and fish oil supplements helps with infl

The body needs fatty acids to survive and is able to make all but two of them: linoleic acid (LA), in the omega-6 family, and alpha-linolenic acid (ALA) in the omega-3 family. These two fatty acids must be supplied by the diet and are therefore considered essential fatty acids (EFAs). Omega-3 fatty acids, found in coldwater fish (and fish oil), perilla and flaxseed oils, are essential elements of a healthy diet. Omega-3 oils contain eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are usually lacking in the typical Western diet, which is filled with foods containing high amounts of omega-6 fats.30 EPA and DHA can be synthesized in the body from ALA, but EPA and DHA synthesis may be insufficient under certain conditions and for most people that consume Western diets. Studies associate the Mediterranean diet - rich in omega-3 fatty acids, monounsaturated fatty acids such as that found in olive oil, and antioxidant-rich fruits, vegetables, and herbs with lowered cardiovascular risk and increased life span. Other studies support omega-3?s importance in cardiovascular health. Life Extension?s Super Omega-3 is a premium, scientifically-validated fish oil concentrate, derived from sustainable sources, that contains a proprietary, full-spectrum blend of synergistic nutrients to provide scientifically-validated cardioprotective health benefits. An abundance of scientific research substantiates the wide-ranging health benefits of omega-3 fatty acids in fish oil and monounsaturated fatty acid and polyphe-nols in olive fruit. No other commercially available fish oil supplement contains this level of essential fatty acids, sesame lignans and olive fruit polyphenols. Super Omega-3 from Life Extension uses a proprietary EPA/DHA technology that results in a pure, stable and easy-to-tolerate fish oil extract. The Pure+ fish oil used in Super Omega-3 is produced with a proprietary technology that purifies the oil with a highly advanced distillation process to reduce environmental pollutants to extremely low levels. The result is an improved fish oil that exceeds the standards set by international rating agencies. The unstable nature of fatty acids like fish oil limits their biological efficacy in the body. Scientific studies show that when sesame lignans are supplemented with fish oil, the beneficial effects are augmented. Sesame lignans help guard against lipid peroxidation, thereby extending the stability of DHA in the body. These lignans also direct fatty acids toward pathways which can help with inflammatory reactions. Super Omega-3 provides standardized sesame lignans to enhance the overall benefits of the improved EPA/DHA fish oil blend. To emulate a Mediterranean diet, Super Omega-3 provides a standardized olive fruit extract to deliver the polyphenol hydroxytyrosol, a powerful antioxidant that protects normal LDL from oxidation and counters dangerous free radicals. Research shows that a combination of olive oil and fish oil supplements hel

The body needs fatty acids to survive and is able to make all but two of them: linoleic acid (LA), in the omega-6 family, and alpha-linolenic acid (ALA) in the omega-3 family. These two fatty acids must be supplied by the diet and are therefore considered essential fatty acids (EFAs). Omega-3 fatty acids, found in coldwater fish (and fish oil), perilla and flaxseed oils, are essential elements of a healthy diet. Omega-3 oils contain eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are usually lacking in the typical Western diet, which is filled with foods containing high amounts of omega-6 fats. EPA and DHA can be synthesized in the body from ALA, but EPA and DHA synthesis may be insufficient under certain conditions and for most people that consume Western diets. Studies associate the Mediterranean diet - rich in omega-3 fatty acids, monounsaturated fatty acids such as that found in olive oil, and antioxidant-rich fruits, vegetables, and herbs - with lowered cardiovascular risk and increased life span. Other studies support omega-3?s importance in cardiovascular health. Life Extension?s Super Omega-3 is a premium, scientifically-validated fish oil concentrate, derived from sustainable sources, that contains a proprietary, full-spectrum blend of synergistic nutrients to provide scientifically-validated cardioprotective health benefits. An abundance of scientific research substantiates the wide-ranging health benefits of omega-3 fatty acids in fish oil and monounsaturated fatty acid and polyphenols in olive fruit. No other commercially available fish oil supplement contains this level of essential fatty acids, sesame lignans and olive fruit polyphenols. To ensure the purest, most stable, and easy-to-tolerate fish oil supplement, Life Extension Super Omega-3 EPA/DHA is molecularly distilled. This proprietary technology ensures any environmental pollutants are reduced to extremely low levels. Our fish oil enjoys a 5-star rating for purity, quality and concentration from the International Fish Oil Standards program (IFOS). The unstable nature of fatty acids like fish oil limits their biological efficacy in the body. Scientific studies show that when sesame lignans are supplemented with fish oil, the beneficial effects are augmented. Sesame lignans help guard against lipid peroxidation, thereby extending the stability of DHA in the body. These lignans also direct fatty acids toward pathways which can help with inflammatory reactions. Super Omega-3 provides standardized sesame lignans to enhance the overall benefits of the improved EPA/DHA fish oil blend. To emulate a Mediterranean diet, Super Omega-3 provides a standardized olive fruit extract to deliver the polyphenol hydroxytyrosol, a powerful antioxidant that protects normal LDL from oxidation and counters dangerous free radicals. Research shows that a combination of olive oil and fish oil supplements helps with inflammation better than a placebo or fish oil alone. Therefore, Super

Lipoic acid helps protect against oxidative stress generated by high glucose levels. Alpha-lipoic acid consists of two different forms (isomers) that have vastly different properties. The ?R? form is the biologically active component (native to the body) that is responsible for lipoic acid?s phenomenal antioxidant effect. The ?S? form is produced from chemical manufacture and is not very biologically active. Typical alpha-lipoic acid supplements consist of the ?R? and ?S? form in a 50/50 ratio. That means a 100 mg alpha-lipoic acid supplement is providing 50 mg of the biologically active ?R? form. The human body normally produces and uses the ?R? form of lipoic acid. This active form, R-lipoic acid , significantly supports healthy inflammatory response, is a potent free-radical scavenger and has been shown to be more potent than the combined ?R? and ?S? forms that comprise most alpha-lipoic acid supplements. Life Extension is continually searching for innovative nutritional technologies. Through dedicated research and development, the newer form of R-lipoic acid is being seen as the ?next-generation? antioxidant powerhouse. Life Extension?s Super R-Lipoic Acid has demonstrated superior bioavailability, stability, and potency for a variety of health benefits. This breakthrough converts the biologically active ?R? form of lipoic acid to sodium-R-lipoic acid, which, in a recent human study achieved 10?30 times higher peak blood levels than pure R-lipoic acid. Not only does this newer lipoic acid formulation reach higher peak blood levels, it also achieves them sooner, ensuring rapid uptake from the plasma into the tissues. A recent study showed that oral ingestion of Super R-Lipoic Acid reached peak plasma concentrations within just 10?20 minutes of supplementation. Unlike other forms of lipoic acid, Super R-Lipoic Acid is more stable in the body. The increased stability of this enhanced formulation is the reason for its greater absorption and bioavailability compared with R-lipoic acid. The superior antioxidant effects of R-lipoic acid are already well known for supporting healthy mitochondrial function. Now, Super R-Lipoic Acid provides even more potent benefits for preserving youthful cellular energy levels.

Published studies suggest that a remarkably high percentage of men will endure some form of prostate-induced discomfort over the course of their lifetimes. Decades of research substantiate saw palmetto as the gold standard in natural prostate support. Through a novel scientific advance, Life Extension now offers an ultra high-potency formula unlike typical saw palmetto extracts. The saw palmetto berry ( Serenoa repens ) is rich in bioactive, high-molecular weight compounds including beta-sitosterol. It has been shown to interfere with DHT activity in the prostate, inhibit alpha-adrenergic receptor activity (to support normal urinary flow), and help regulate inflammatory actions in the prostate gland. DeepExtract is a patented, ultra-high pressure CO2 technology engineered to recover far greater amounts of bioactive, high-molecular weight fatty acids from the saw palmetto berry during the extraction process. The result is a superior formula containing key ingredients in higher concentrations than many other extracts. These naturally occurring substances are left behind by more widely used low-pressure CO2 extraction techniques. DeepExtract ensures the most desirable and complete bioactive extract profile available. The result is a formula that most closely resembles the composition of premium, mature saw palmetto berries. This saw palmetto extract has been standardized to contain 85% free fatty acids and sterols. A high-potency phytosterol complex has also been added to supply a natural ratio of concentrated plant sterols (including beta-sitosterol) derived from vegetable and seed oils such as soybean, rapeseed, sunflower seed, and corn.

Published studies suggest that a remarkably high percentage of men will endure some form of prostate-induced discomfort over the course of their lifetimes. Decades of research substantiate saw palmetto as the gold standard in natural prostate support. Through a novel scientific advance, Life Extension now offers an ultra high-potency formula unlike typical saw palmetto extracts. The saw palmetto berry ( Serenoa repens ) is rich in bioactive, high-molecular weight compounds including beta-sitosterol . It has been shown to interfere with DHT activity in the prostate, inhibit alpha-adrenergic receptor activity (to support normal urinary flow), and help control inflammatory actions in the prostate gland. DeepExtract is a patented, state-of-the-art, ultra-high pressure CO2 extraction technology that ensures the most complete bioactive extract profile available that most closely reflects the composition of premium, mature saw palmetto berries. The result is a superior formula containing key ingredients in higher concentrations than many other extracts. These naturally occurring substances are left behind by more widely used low-pressure CO2 extraction techniques. DeepExtract ensures the most desirable and complete bioactive extract profile available. The result is a formula that most closely resembles the composition of premium , mature saw palmetto berries . Super Saw Palmetto/Nettle Root Formula with Beta-Sitosterol combines the USPlus saw palmetto CO2 DeepExtract with a nettle root extract (Urtica dioica) , boron, and rosemary to support a healthy prostate. Testosterone converts to estrogen at higher rates as men age. Prostate cells are sensitive to estrogen's growth stimulatory effects. Nettle root helps support prostate cells against the excess estrogen levels. This saw palmetto extract has been standardized to contain 85% free fatty acids and sterols. The phytosterol complex contains a natural ratio of concentrated plant sterols derived from vegetable and seed oils such as soybean, rapeseed, sunflower seed, and corn.

Selenium is a trace mineral that is essential to optimal health. Few people?including physicians?realize that selenium is available in several different forms. Each form of selenium acts along a different pathway to support healthy cell division. For optimized selenium support, one should supple­ment with all three of the following forms of selenium: Sodium selenite L-selenomethionine Selenium-methyl L-selenocysteine Life Extension has upgraded Super Selenium Complex with a new selenium blend that combines all three of these unique forms of selenium. A small amount of vitamin E is included because it has been shown to work synergistically with selenium. Studies suggest selenium deficiency can pose a signifi­cant health risk. For example, the body utilizes selenium to make gluta­thione peroxidase, an endogenous antioxidant enzyme almost as important as SOD (superoxide dismutase). Selenium also supports normal thyroid and immune function in healthy individuals.